BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a member of the polycomb group genes. BMI1 and Ring1 together greatly increase the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. By repressing the p16Ink4a and p19Arf genes, BMI1 has an important part in the regulation of cell proliferation and senescence. This gene is also necessary for maintenance of adult hematopoietic and neural stem cells. Diseases associated with BMI1 include embryonal cancer and erythroplakia.
BMI1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recombinant Protein of Human BMI1
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
PCGF4, RNF51, FLVI2/BMI1
WB, IHC, IF, IP; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:20 - 1:50 IP 1:20 - 1:50