5-Aza-2'-deoxycytidine

Alternative Names
Decitabine; 5-Aza-2'-deoxy-D-cytidine

Description
5-Aza-2'-deoxycytidine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling "opening" chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.

CAS Number
2353-33-5

Chemical Formula
C₈H₁₂N₄O₄

Molecular Weight
228.2

Size
50 mg

Purity
>95%

Solubility
50% Acetic acid or DMSO

Storage Temp
-20°C