LoadingLoading
  • Browse By Category

  • Products
  • Services
  • Support
  • Corporate
  • Back
  • Products

  • Antibodies
  • Instruments
  • Research Kits
  • Proteins & Enzymes
  • Peptides
  • COVID-19 Assays
  • Back
  • Antibodies

  • Primary Antibodies
  • Secondary Antibodies
  • Tag Antibodies
  • Antibody Panel Packs
  • Back
  • Primary Antibodies

  • DNA Methylation Antibodies
  • Cell Structure & Function Antibodies
  • RNA Processing & Modification Antibodies
  • Chromatin & Transcription Antibodies
  • Other Primary Antibodies
  • Histone Modification Antibodies
  • Signal Transduction Antibodies
  • Metabolism Antibodies
  • Immunology & Inflammation Antibodies
  • Back
  • Cell Structure & Function Antibodies

  • DNA Damage & Repair Antibodies
  • Apoptosis & Cell Death Antibodies
  • Cell Cycle Antibodies
  • Cellular Structure Antibodies
  • Trafficking Antibodies
  • Back
  • Chromatin & Transcription Antibodies

  • DNA Replication & Transcription Antibodies
  • Chromatin Remodeling Antibodies
  • Cell Growth Antibodies
  • Development & Differentiation Antibodies
  • Back
  • Histone Modification Antibodies

  • Histone Methylation (Lysine) Antibodies
  • Histone Acetylation Antibodies
  • Histone Phosphorylation Antibodies
  • Ubiquitination & SUMOylation Antibodies
  • Histone Methylation (Arginine) Antibodies
  • Other Histone Methylation Antibodies
  • Other Histone Acetylation Antibodies
  • Histone Deacetylation Antibodies
  • Other Histone Antibodies
  • Back
  • Signal Transduction Antibodies

  • Cell Surface Receptor & Kinase Antibodies
  • Intracellular Kinase & Adaptor Protein Antibodies
  • Phosphatase Antibodies
  • Secreted Growth Factor Antibodies
  • Back
  • Metabolism Antibodies

  • Glucose Metabolism Antibodies
  • Lipid Metabolism Antibodies
  • Protein Metabolism Antibodies
  • Nucleotide Metabolism Antibodies
  • Back
  • Immunology & Inflammation Antibodies

  • Cell Marker & Receptor Antibodies
  • Cytokine Antibodies
  • Other Immunology Antibodies
  • Back
  • Antibody Panel Packs

  • Histone Modification
  • DNA Methylation
  • Back
  • Instruments

  • Sonication Devices
  • Magnets & Sample Mixers
  • Back
  • Research Kits

  • DNA Methylation
  • Chromatin & Transcription
  • Histone Methylation
  • Acetylation & Deacetylation
  • Gene Editing & Silencing
  • Sample Preparation
  • DNA Damage & Repair
  • Next Generation Sequencing
  • RNA Methylation
  • Other Histone Modifications
  • Back
  • DNA Methylation

  • DNA Bisulfite Conversion
  • DNA Methylation Quantification
  • DNA Methyltransferase & Demethylase Assays
  • Methylated DNA Immunoprecipitation
  • Methylated DNA Amplification
  • Back
  • Chromatin & Transcription

  • General Chromatin Immunoprecipitation
  • In Vitro Protein-DNA Interaction
  • Methyl-Histone Chromatin IP
  • Acetyl-Histone Chromatin IP
  • Methyl-DNA Binding Protein ChIP
  • Chromatin Analysis
  • Back
  • Histone Methylation

  • Histone Methyltransferase Assay
  • Histone Methylation Quantification
  • Histone Demethylase Assay
  • Back
  • Acetylation & Deacetylation

  • Histone Acetyltransferase (HAT) Assay
  • Histone Deacetylase (HDAC) Assay
  • Histone Acetylation Quantification
  • Back
  • Sample Preparation

  • DNA Preparation
  • Protein Preparation
  • Chromatin Preparation
  • RNA Preparation
  • Back
  • Other Histone Modifications

  • Sumoylation
  • Histone Phosphorylation Assay
  • Histone Citrullination
  • Back
  • Proteins & Enzymes

  • DNA Methylation/Demethylation Proteins
  • Methylated DNA Binding Proteins
  • Unmodified Histone Proteins
  • Chromatin Binding/Transcription Proteins
  • ADP Ribose Proteins
  • DNA Damage & Repair Proteins
  • Modified Histone Proteins
  • Back
  • DNA Methylation/Demethylation Proteins

  • DNA Demethylation Proteins
  • DNA Methylation Proteins
  • Back
  • Modified Histone Proteins

  • Histone Methylation Proteins
  • Histone Demethylation Proteins
  • Histone Acetylation Proteins
  • Histone Deacetylation Proteins
  • Histone Phosphorylation Proteins
  • Histone Sumoylation Proteins
  • Back
  • Peptides

  • Histone Methylation Peptides
  • Histone Acetylation Peptides
  • Histone Phosphorylation Peptides
  • Back
  • COVID-19 Assays

  • COVID-19 Kits
  • COVID-19 Antibodies
  • COVID-19 Proteins
  • Back
  • Services

  • DNA-based NGS Services
  • Chromatin-based NGS Services
  • qPCR-based Services
  • ELISA-based Services
  • Back
  • DNA-based NGS Services

  • Reduced Representation Bisulfite Sequencing (RRBS)
  • Whole Genome Bisulfite Sequencing (WGBS)
  • Targeted Bisulfite Sequencing
  • Back
  • Chromatin-based NGS Services

  • ChIP Sequencing (Histone Modifications)
  • Back
  • qPCR-based Services

  • Methylation-Specific qPCR (MSP)
  • Back
  • ELISA-based Services

  • Global DNA 5-mC Quantification
  • Global DNA 5-hmC Quantification
  • Global RNA 5-mC Quantification
  • Global RNA m6A Quantification
  • Histone Modification Quantification
  • Back
  • Support

  • Technical Support
  • Quality Assurance
  • Resources
  • Back
  • Technical Support

  • Submit Support Ticket
  • Back
  • Quality Assurance

  • Epigentek Gurantee
  • Risk-Free Testing: Pioneer Program
  • Product Review Program
  • Back
  • Resources

  • Epigenetics Newsletter
  • Intro to Epigenetics
  • What is Epigenetics?
  • Back
  • Corporate

  • Company Information
  • Procurement
  • Communication
  • Back
  • Company Information

  • About Epigentek
  • Press Release
  • Career Opportunities
  • Back
  • Procurement

  • Ordering Information
  • New Lab Startup Program
  • Distributors & Resellers
  • Back
  • Communication

  • Contact Us
  • Customer Feedback Survey
  • Events Calendar
Epigentek Home
Cart (0)
Track
Account
  • Products

    Antibodies

    • DNA Methylation
    • Histone Modification
      • Histone Methylation (Lysine)
      • Histone Methylation (Arginine)
      • Other Histone Methylation
      • Histone Acetylation
      • Histone Deacetylation
      • Other Histone Acetylation
      • Histone Phosphorylation
      • Ubiquitination & SUMOylation
      • Other Histone Antibodies
    • RNA Processing & Modification
    • Chromatin & Transcription
      • Chromatin Remodeling
      • DNA Replication & Transcription
      • Cell Growth
      • Development & Differentiation
    • Cell Structure & Function
      • Cell Cycle
      • DNA Damage & Repair
      • Apoptosis & Cell Death
      • Cellular Structure
      • Trafficking
    • Signal Transduction
      • Cell Surface Receptor & Kinase
      • Intracellular Kinase & Adaptor Protein
      • Phosphatase
      • Secreted Growth Factor
    • Metabolism
      • Glucose Metabolism
      • Lipid Metabolism
      • Protein Metabolism
      • Nucleotide Metabolism
    • Immunology & Inflammation
      • Cell Marker & Receptor
      • Cytokine
      • Other Immunology Antibodies
    • Other Primary Antibodies

    • Secondary Antibodies
    • Tag Antibodies
    • Antibody Panel Packs
      • Histone Modification Panel
      • DNA Methylation Panel

    Research Kits

    • Sample Preparation
      • DNA Preparation
      • RNA Preparation
      • Protein Preparation
      • Chromatin Preparation
    • Next Generation Sequencing
    • DNA Methylation
      • DNA Bisulfite Conversion
      • DNA Methylation Quantification
      • Methylated DNA Immunoprecipitation (meDIP)
      • DNMT & DNA Demethylase Assay
      • Methylated DNA Amplification
    • RNA Methylation
    • Chromatin & Transcription
      • Chromatin Immunoprecipitation
      • ChIP-seq
      • CUT&RUN
      • In Vitro Protein-DNA Interaction
      • Chromatin Accessibility
    • Histone Methylation
      • Histone Methylation Quantification
      • Histone Methytransferase Assay
      • Histone Demethylase Assay
    • Histone Acetylation
      • Histone Acetylation Quantification
      • Histone Acetylase (HAT) Assay
      • Histone Deacetylase (HDAC) Assay
    • Other Histone Modifications
      • Histone Citrullination
      • Histone Phosphorylation
      • SUMOylation
    • DNA Damage & Repair
    • Gene Editing & Silencing

    Proteins & Enzymes

    • DNA Methylation
      • DNA Methylation
      • DNA Demethylation
    • Modified Histones
      • Histone Methylation
      • Histone Demethylation
      • Histone Acetylation
      • Histone Deacetylation
      • Histone Phosphorylation
      • Histone SUMOylation
    • Unmodified Histones
    • Methylated DNA Binding
    • ADP Ribose
    • Chromatin Binding/Transcription
    • DNA Damage & Repair

    Peptides

    • Histone Methylation
    • Histone Acetylation/Deacetylation
    • Histone Phosphorylation

    Instruments

    • Sonication Devices
    • Magnets & Sample Mixers

    COVID-19 Assays

    • COVID-19 Kits
    • COVID-19 Antibodies
    • COVID-19 Proteins
  • Services

    DNA-based NGS Services

    • Reduced Representation Bisulfite Sequencing (RRBS)
    • Whole Genome Bisulfite Sequencing (WGBS)
    • Targeted Bisulfite Sequencing

    Chromatin-based NGS Services

    • ChIP Sequencing (Histone Modifications)

    qPCR-based Services

    • Methylation-Specific qPCR (MSP)

    ELISA-based Services

    • Global DNA 5-mC Quantification
    • Global DNA 5-hmC Quantification
    • Global RNA 5-mC Quantification
    • Global RNA m6A Quantification
    • Histone Modification Quantification
  • Support

    Technical Support

    • Submit Support Ticket
    • Download Datasheet

    Quality Assurance

    • EpigenTek Guarantee
    • Risk-Free Testing: Pioneer Program
    • Product Review Program

    Resources

    • Epigenetics Newsletter
    • Intro to Epigenetics
    • What Is Epigenetics?
  • Corporate

    Company Information

    • About EpigenTek
    • Corporate Sustainability
    • Press Releases
    • Career Opportunities

    Procurement

    • Ordering Information
    • New Lab Startup Program
    • Distributors & Resellers

    Communication

    • Contact Us
    • Customer Feedback Survey
    • Events Calendar
 
EpiGentek Guarantee
   Home  »  Modulators & Inhibitors 
  Quote Lookup

Modulators & Inhibitors

DNA Methylation
DNA methylation modulators and inhibitors are useful for studying the common epigenetic mechanism known as DNA methylation, which entails the addition of a methyl group onto DNA. Using enzyme inhibition assays, various DNA methylation modulators and inhibitors have been shown to display antitumor and antioxidant properties, inhibit telomerase and DNA methyltransferase (DNMT) activity, and block activation of various receptors.

Histone Acetylation
Modulators and inhibitors are used in enzyme inhibition assays to study histone acetylation, or the addition of an acetyl group on a histone, which then affects the regulation of transcription through chromatin remodeling. Certain epigenetic modulators and inhibitors specific to histone acetylation studies have been shown to inhibit histone acetyltransferases (HATs) such as p300/CBP associated factor histone acetyltransferase, inhibit the transcription factor NF kappa B, promote apoptosis thr...

Histone Deacetylation
Modulators and inhibitors are used in enzyme inhibition assays to study histone deacetylation, or the removal of an acetyl group on a histone, which impacts the regulation of DNA expression. Histone deacetylation modulators and inhibitors inhibit histone deacetylases (HDACs) also called lysine deacetylases (KDACs). They are crucial to advancing epigenetic research in cell cycle regulation, cell proliferation, and development of cancer.

Histone Demethylation
Histone demethylation is defined as the removal of methyl groups from histone proteins by histone demethylases (KDMs), which affects the inactivation of chromatin and therefore gene expression. Histone demethylation modulators and inhibitors inhibit histone demethylases (HDMs) and offer insight into diseases such as breast cancer, prostate cancer, and lung cancer that are related to histone demethylation.

Histone Methylation
Histone methylation is described as the transfer of methyl groups to histone proteins (commonly H3 and H4) by histone methyltransferases (HMTs), which affects the activation of chromatin and therefore gene expression. Histone methylation modulators and inhibitors inhibit histone methyltransferases and allow researchers to study diseases, especially cancer, that are related to histone methylation.

Histone Phosphorylation
Histone phosphorylation has been implicated in numerous processes such as transcription, DNA repair, cell cycle progression and apoptosis, and chromosome condensation. These histone phosphorylation modulators and inhibitors act to inhibit proteases and phosphatases for research investigating diseases connected to phosphorylation such as Alzheimer’s and Huntington’s disease.

Result Pages:  1  2  [Next >>]  Displaying 1 to 20 (of 22 products)
Image Description Cat. No. Size Price
5-Aza-2'-deoxycytidine
5-Aza-2'-deoxycytidine

Citations (2)
Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: DNA Methylation
Solubility: DMSO
M22000-150 mg $162.00 Discontinued
Modulators & Inhibitors
5-Azacytidine
5-Azacytidine

Citations (1)
Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: DNA Methylation
Solubility: DMSO
M22001-11 g $102.00 Discontinued
Modulators & Inhibitors
Anacardic Acid
Anacardic Acid

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO, Ethanol, Other
M37000-15 mg $92.00 Discontinued
Modulators & Inhibitors
APHA Compound 8
APHA Compound 8

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO
M45003-11 mg $162.00 Discontinued
Modulators & Inhibitors
Aurora A Inhibitor I
Aurora A Inhibitor I

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Phosphorylation
Solubility: DMSO
M75000-15 mg $619.00 Discontinued
Modulators & Inhibitors
C646, p300/CBP Inhibitor
C646, p300/CBP Inhibitor

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO
M31000-11 mg $168.00 Discontinued
Modulators & Inhibitors
Cambinol
Cambinol

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO, Ethanol
M47000-15 mg $449.00 Discontinued
Modulators & Inhibitors
Curcumin
Curcumin

Citations (1)
Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO, Ethanol, Other, Water
M35000-11 g $41.00 Discontinued
Modulators & Inhibitors
DPQ
DPQ

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Phosphorylation
Solubility: DMSO
M71000-11 mg $129.00 Discontinued
Modulators & Inhibitors
DR2313
DR2313

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Phosphorylation
Solubility: Water
M75002-110 mg $140.00 Discontinued
Modulators & Inhibitors
Epigallocatechin Gallate
Epigallocatechin Gallate

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: DNA Methylation
Solubility: DMSO, Ethanol
M21000-150 mg $102.00 Discontinued
Modulators & Inhibitors
Ginkgolic acid
Ginkgolic acid

Application: Enzyme Activation
Molecular Weight: 100-500
Research Area: Histone Phosphorylation
Solubility: DMSO, Ethanol
M75004-15 mg $449.00 Discontinued
Modulators & Inhibitors
MLN8237 (Alisertib)
MLN8237 (Alisertib)

Application: Enzyme Inhibition
Molecular Weight: >500
Research Area: Histone Phosphorylation
Solubility: DMSO, Ethanol, Water
M76000-15 mg $261.00 Discontinued
Modulators & Inhibitors
Pargyline
Pargyline

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Methylation
Solubility: DMSO, Ethanol, Water
M55001-1500 mg $101.00 Discontinued
Modulators & Inhibitors
SAHA
SAHA

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO, Ethanol
M41000-210 mg $88.00 Discontinued
Modulators & Inhibitors
Sodium Butyrate
Sodium Butyrate

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: Water
M41001-11 g $271.00 Discontinued
Modulators & Inhibitors
Splitomicin
Splitomicin

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO
M45001-15 mg $261.00 Discontinued
Modulators & Inhibitors
Trans-2-Phenylcyclopropylamine hydrochloride
Trans-2-Phenylcyclopropylamine hydrochloride

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Methylation
Solubility: DMSO, Water
M55000-1250 mg $101.00 Discontinued
Modulators & Inhibitors
Trichostatin A
Trichostatin A

Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO, Ethanol, Other
M45000-11 mg $205.00 Discontinued
Modulators & Inhibitors
Valproic Acid
Valproic Acid

Citations (1) | (1)
Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: Water
Modulators & Inhibitors
Result Pages:  1  2  [Next >>]  Displaying 1 to 20 (of 22 products)
BOGO-Conjugate Abs
Featured Areas of Study
DNA, Protein, & Chromatin Preparation
DNA Methylation & Demethylation Analysis
Chromatin Immunoprecipitation
Histone Methylation & Demethylation
Histone Acetylation & Deacetylation
Gene Expression & Silencing
DNA Damage & Repair
Histone Phosphorylation
SUMOylation
Next-Generation Sequencing
Products & Services
Ordering Information & Return Policy
Epigenetic Services
Discounts & Promotions
Rewards Program
Product Reviews
New Lab Startup Program
Risk-Free Testing: Pioneer Program

Support
Download Datasheets
Epigentek Guarantee
Technical Support
Corporate
About Epigentek
Press Releases
Product Newsletter
Events Calendar
Distributors & Resellers
EpigenCare
Career Opportunities
Contact Us

Stay Informed



Terms & Conditions | Privacy Policy | Site Map
Copyright © EpiGentek Group Inc. All rights reserved.
  • Stay Informed:
Terms & Conditions | Privacy Policy Copyright © 2020 EpiGentek
➤