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C646, p300/CBP Inhibitor

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Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO
100% Guarantee: 6 months
Catalog No.SizePriceQty
M31000-11 mg $168.00  Discontinued
Availability: Discontinued 
Product Overview

Alternative Names
(E)-4-(4-((5-(4,5-Dimethyl-2-nitrophenyl)furan-2-yl)-methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid

Description
Cell-permeable. A reversible, p300/CBP (CREB-binding protein) histone acetyltransferase (HAT) inhibitor (Ki = 400 nM). Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Suppresses histone H3 and H4 acetylation in mouse fibroblast cell lines.

CAS Number
328968-36-1

Chemical Formula
C24H19N3O6

Molecular Weight
445.4

Size
1 mg

Purity
≥98% by NMR

Solubility
DMSO (25 mM)

Storage Temp
-20°C

User Guide & MSDS

[User Guide]*
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