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Valproic Acid

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Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: Water
100% Guarantee: 6 months
Availability: Discontinued 
Product Overview

Alternative Names
Valproic acid sodium, valproic acid sodium salt, valproic acid salt, valproate sodium, sodium valproate, VPA

Description
A cell-permeable histone deacetylase 1 (HDAC1) inhibitor (IC50 = 400 µM) in sodium salt powder format that exhibits anticancer, anti-inflammatory and neuroprotective properties. Recently it has been reported that valproic acid enables reprogramming of primary human fibroblasts with only two factors, Oct4 and Sox2, without the need for the oncogenes c-Myc or Klf4

CAS Number
1069-66-5

Chemical Formula
C8H15O2Na

Molecular Weight
166.19

Size
500 mg

Purity
≥98% by titration

Solubility
H2O (100 mM)

Storage Temp
-20°C

User Guide & MSDS

[User Guide]*
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Product Citations

Inoue K et. al. (February 2019). Podocyte histone deacetylase activity regulates murine and human glomerular diseases. J Clin Invest.

Customer Reviews

Rating by s***********@yale.edu Verified Purchase Reviewed on: Monday 19 December, 2016
Application Description
Used to treat mice after kidney injury

Pros: High quality product
Cons: none
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