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SMYD3 Polyclonal Antibody

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Western blot analysis of extracts of various cell lines, using SMYD3 Polyclonal Antibody.
Application: FC, WB
Areas of Research: Other Histone Modification
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-3731-05050 µl $266.00  Discontinued
A-3731-100100 µl $465.00 
Availability: Usually Ships in 3-4 Days 
Product Overview

Background
SMYD3 (SET and MYND domain containing 3) is a member of the SMYD family of protein methyltransferases. All family members (SMYD1, SMYD2, SMYD3, SMYD4, and SMYD5) contain a conserved catalytic SET domain, first identified in Drosophila Su[var]3-9, Enhancer of zeste, and Trithorax proteins. SMYD3 can be overexpressed in several different cancers, including breast, colorectal, and liver cancer. Research shows that cancer cells may express full-length and a more active cleaved SMYD3 that lack the first 34 amino acids at the N-terminus. The N-terminus of full-length of this gene interacts with Hsp90alpha and enhances its activity. This indicates that the N-terminal region may participate in regulating methyltransferase activity.

Description
SMYD3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Specificity
Human

Isotype
IgG

Uniprot ID
Q9H7B4

Purification
Affinity Purified

Immunogen
Synthetic Peptide of Human SMYD3

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
KMT3E, ZMYND1, ZNFN3A1, bA74P14.1

Application
WB, FC

User Guide & MSDS

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