BackgroundHistone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3 (H3K4me and H3K36me). Acts as a transcriptional activator. Plays an important role in the transcriptional regulation of muscle cell differentiation via interaction with MYOD1.
DescriptionSETD3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ86TU7
Purification>95%, Protein G purified
ImmunogenRecombinant Human Histone-lysine N-methyltransferase setd3 protein (166-265AA)
StorageShipped at 4°C. Upon receipt, store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesHistone-lysine N-methyltransferase setd3, SET domain-containing protein 3, SETD3, C14orf154
ApplicationELISA, IHC; Recommended dilution: IHC: 1:200-1:500
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