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RNF20 Monoclonal Antibody

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Western blot analysis of extracts of various cell lines, using RNF20 Monoclonal Antibody.
Application: WB
Areas of Research: Chromatin Remodeling
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-2713-05050 µg $266.00  Discontinued
A-2713-100100 µl $465.00 
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Product Overview

Background
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).

Description
RNF20 Monoclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. PBS with 0.02% sodium azide, pH7.3.

Specificity
Human

Isotype
IgG

Purification
Affinity Purified

Immunogen
Synthetic Peptide of Human RNF20

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
BRE1, BRE1A, hBRE1

Application
WB; Recommended dilution: WB 1:200 - 1:500

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