This product was discontinued; sorry for the inconvenience. We recommend the following: Cat.# A51361.
BackgroundThis gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
DescriptionPOLG2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ9UHN1
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human POLG2 (NP_009146.2).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesPOLG2; HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB; DNA polymerase gamma 2, accessory subunit
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000