PDCD10 Polyclonal Antibody

This product was discontinued; sorry for the inconvenience. We recommend the following: Cat.# A57153.

Background
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Description
PDCD10 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Rat

Isotype
IgG

Uniprot ID
Q9BUL8

Purification
Affinity Purification

Immunogen
A synthetic peptide of human PDCD10

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
PDCD10; CCM3; TFAR15; programmed cell death 10

Application
IHC; Recommended dilution: IHC 1:50 - 1:100