Please see "Related Products" for an equivalent antibody.
BackgroundNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
DescriptionNF-kB p65 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ04206
PurificationAffinity Purified
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 450-550 of human NF-kB p65 (NP_068810.3).
StorageShipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.
Alternative NamesNFKB3; p65; NF-kB p65; RELA; CMCU
ApplicationWB; Recommended dilution: WB 1:500 - 1:1000