BackgroundDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Methyl-CpG binding domain protein 4 (MBD4), which can bind to methylated DNA in vivo and in vitro, may serve as a methylation-dependent transcriptional repressor.
Concentration0.2 mg/ml
DescriptionRabbit polyclonal antibody to MBD4, ChIP-grade
PurificationProtein A purified
SpecificityMouse, rat, human
IsotypeIgG
Formulation0.1% Sodium Azide, 0.1% Gelatin, PBS
Storage4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
ApplicationWB: 1:200-1:500; IF: 1:100-1: 500, ELISA: 1:1000-1:2000; IP: 2 µg/106 cells