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Global 5mC ELISA
Cell Structure & Function Antibodies

Cell Structure & Function Antibodies

Cell structure & function antibodies are used for investigating cell structure and function and include those linked to DNA damage & repair, cell cycle, apoptosis, cellular structure, and trafficking. Cell structure and function antibodies can be used to connect structural features of the cell, such as the cytoskeleton, including microtubules and microfilament, to their function. Cell cycle antibodies are targeted against proteins involved in the steps of the cell cycle, including the interphase and mitotic phase. Proteins such as histone H3 Ser28 are modified as the cell carries out the cell cycle phases during mitosis. Apoptosis, or programmed cell death, can be investigated using antibodies directed against proteins involved in the destruction of cells, such as caspases which are the major regulators of apoptosis. DNA damage and repair antibodies give insight into damage of DNA that disrupts gene expression and the processes involved in mending these damages.
Cell Cycle Antibodies
The cell cycle constitutes a series of stages that allow a cell to double its cellular components and divide into two daughter cells. Cell cycle and division are crucial for development of a multicellular organism, as well as for cell-renewal in regenerating tissue. Actively proliferating cells undergo four phases during cell division or mitosis.

DNA Damage & Repair Antibodies
Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

Apoptosis & Cell Death Antibodies
Programmed cell death is important for normal physiological functioning, it is crucial in wound healing, development, differentiation and immune responses. However, unregulated cell death can lead to development of several diseases. Several forms of cell death include apoptosis, necrosis, and autophagy, which differ mainly in the cells morphological changes that accompany them, as well as the proteins involved in their activation and execution.

Cellular Structure Antibodies
Structural proteins are involved in maintenance of cellular structures and are crucial in cell polarity, cell to cell communication, movement and migration, cell division and other functions requiring cell malleability. Structural differences among cell types are crucial for cells to perform their specialized functional roles. Structural proteins are fibrous proteins, and include keratins, actin, collagens, and tubulins among others.

Trafficking Antibodies
Cells must transport proteins from the endoplasmic reticulum in the cytoplasm, where they are mostly synthesized, to the nucleus, plasma membrane or other sites where they will ultimately perform their functions, and they should recycle back membrane and extracellular components. Intracellular trafficking involves two major pathways, the exocytic pathway, which transports components from the inside to the outside of the cell, and the endocytic pathway which transports material from the outside to the inside of the cell. Integral membrane proteins and secreted proteins are transported to the cell surface via the exocytic pathway, in which they are carried from the endoplasmic reticulum, to the Golgi apparatus and through secretory vesicles which then fuse with the plasma membrane. On the other hand, some cell surface receptors, after activation and signaling, undergo endocytosis and transport to lysosomes for their degradation, in a series of vesicular bodies called endosomes.

Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 5431 products)
Image Description Cat. No. Size Price
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody

Application: ELISA, IH
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Goat
Isotype: IgG
Purification: Serum
Reactivity: Broad Range, Human, Mouse, Rat
A-6300-10.1 mlView
Antibodies
A20 Monoclonal Antibody [8E8.38]
A20 Monoclonal Antibody [8E8.38]

Application: WB
Areas of Research: Cell Cycle
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1
Purification: Serum
Reactivity: Human
A-0536-05050 µgViewDiscontinued
Antibodies
ABCA9 Polyclonal Antibody
ABCA9 Polyclonal Antibody

Application: ELISA, IF
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66090-05050 µgView
A66090-100100 µgView
Antibodies
ABCA9 Polyclonal Antibody, Biotin Conjugated
ABCA9 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66093-05050 µgView
A66093-100100 µgView
Antibodies
ABCA9 Polyclonal Antibody, FITC Conjugated
ABCA9 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66092-05050 µgView
A66092-100100 µgView
Antibodies
ABCA9 Polyclonal Antibody, HRP Conjugated
ABCA9 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66091-05050 µgView
A66091-100100 µgView
Antibodies
ABCB1 Monoclonal Antibody [1F11]
ABCB1 Monoclonal Antibody [1F11]

Citations (1)
Application: ELISA, WB
Areas of Research: Cell Trafficking
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG1 Kappa
Purification: Affinity Purified
Reactivity: Human
A-6195-100100 µgView
Antibodies
ABCB1 Polyclonal Antibody
ABCB1 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A52229-05050 µgView
A52229-100100 µgView
Antibodies
ABCB1 Polyclonal Antibody, Biotin Conjugated
ABCB1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A52226-05050 µgView
A52226-100100 µgView
Antibodies
ABCB1 Polyclonal Antibody, FITC Conjugated
ABCB1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A52227-05050 µgView
A52227-100100 µgView
Antibodies
ABCB1 Polyclonal Antibody, HRP Conjugated
ABCB1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A52228-05050 µgView
A52228-100100 µgView
Antibodies
Abcb4 Polyclonal Antibody
Abcb4 Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Mouse
A52844-05050 µgView
A52844-100100 µgView
Antibodies
Abcb4 Polyclonal Antibody, Biotin Conjugated
Abcb4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Mouse
A52841-05050 µgView
A52841-100100 µgView
Antibodies
Abcb4 Polyclonal Antibody, FITC Conjugated
Abcb4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Mouse
A52842-05050 µgView
A52842-100100 µgView
Antibodies
Abcb4 Polyclonal Antibody, HRP Conjugated
Abcb4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Mouse
A52843-05050 µgView
A52843-100100 µgView
Antibodies
ABCB5 Polyclonal Antibody
ABCB5 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A57930-05050 µgView
A57930-100100 µgView
Antibodies
ABCB5 Polyclonal Antibody, Biotin Conjugated
ABCB5 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A57931-05050 µgView
A57931-100100 µgView
Antibodies
ABCB5 Polyclonal Antibody, FITC Conjugated
ABCB5 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A57932-05050 µgView
A57932-100100 µgView
Antibodies
ABCB5 Polyclonal Antibody, HRP Conjugated
ABCB5 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Trafficking
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Reactivity: Human
A57933-05050 µgView
A57933-100100 µgView
Antibodies
ABCF2 Monoclonal Antibody [1D11]
ABCF2 Monoclonal Antibody [1D11]

Application: ELISA, IHC, WB
Areas of Research: Cell Trafficking
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG2a Kappa
Purification: Affinity Purified
Reactivity: Human
A-2132-100100 µgView
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 5431 products)
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