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CBX5 Polyclonal Antibody

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Western blot
All lanes: CBX5 Polyclonal Antibody at 9 ug/ml
Lane 1: K562 whole cell lysate
Lane 2: MCF7 whole cell lysate
Lane 3: 293T whole cell lysate
Lane 4: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 22 kDa
Observed band size: 22 kDa
Immunohistochemistry of paraffin-embedded human glioma cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
Application: ELISA, IHC, WB
Areas of Research: Chromatin Remodeling
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A50101-02020 µg $59.00 
A50101-05050 µg $256.00 
A50101-100100 µg $359.00 
Availability: Usually Ships Within 1 Week 
Product Overview

Background
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

Description
CBX5 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
P45973

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Chromobox protein homolog 5 protein (1-191AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, CBX5, HP1A

Application
ELISA, WB, IHC; Recommended dilution: WB:1:500-2000, IHC:1:20-1:200

User Guide & MSDS

[User Guide]*
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