Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein . Defects in ALDOA are the cause of glycogen storage disease type 12 (GSD12) [MIM:611881]; also known as red cell aldolase deficiency. A metabolic disorder associated with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis. Belongs to the class I fructose-bisphosphate aldolase family.
ALDOA Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
Protein G purified
Recombinant Human Fructose-bisphosphate aldolase A protein (2-364AA)
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
ALDOA, ALDA, Lung cancer antigen NY-LU-1, Muscle-type aldolase
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000