SIRT6 Monoclonal Antibody [1D8]

Background
SIRT6 is a member of the sirtuin (silent mating type information regulation 2 homolog) family of proteins which are characterized by a sirtuin core domain and are grouped into 4 class types. Sirtuins share NAD dependency for their enzymatic activity, but some show NAD-dependent deacetylase activity, while others exhibit ADP ribosyltransferase activity or both. Sirtuins may act to influence a wide range of cellular processes such as aging, transcription, apoptosis, inflammation and stress resistance. Seven members make up the family of sirtuins in mammals (SirT1-T7). SIRT6 is a Class IV sirtuin. 

Description
Mouse monoclonal antibody raised against a partial recombinant SIRT6, clone 1D8.

Size
100 µg

Purification
Protein A purified

Immunogen
SIRT6 (NP_057623, 141 a.a. ~ 251 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Cross Reactivity
Human

Isotype
IgG2a Kappa

Formulation
In 1x PBS, pH 7.2

Storage
Aliquot and store at -20ºC or lower. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.

Handling Recommendations
For maximum recovery of the products, centrifuge the vial prior to opening the cap.

Alternative Names
Sirtuin6, 2810449N18Rik antibody, AI043036 antibody, Mono ADP ribosyltransferase sirtuin 6 antibody, NAD-dependent deacetylase sirtuin-6 antibody, Regulatory protein SIR2 homolog antibody, SIR2 like 6 antibody, Sir2 related protein type 6 antibody, SIR2L6 antibody, Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae) antibody, Sirtuin 6 antibody

Applications & Suggested Dilutions*
ELISA: 0.25-1 µg/ml