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PRDM1 Polyclonal Antibody

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Western blot analysis of extracts from JK and Raji cells using PRDM1 Polyclonal Antibody.
Application: ELISA, IHC
Areas of Research: Histone Methylation & Demethylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-2001-05050 µg $253.00  Discontinued
A-2001-100100 µl $433.00  Discontinued
Availability: Discontinued 
Product Overview

Background
PRDM1 is the human homologue to Blimp-1, a transcriptional repressor affecting multiple key target genes for the terminal differentiation of B-cells along the plasma cell lineage. PRDM1 recruits methyltransferases to their targets, inducing methylation and thus transcriptional repression of those gene targets. Also, the PRDM1 protein binds specifically to the positive regulatory domain I element (PRDI) of the beta-IFN gene promoter. It was also recently demonstrated that PRDM1 plays a tumor suppressor role in diffuse large B- cell lymphomas. 

Concentration
Inquire

Description
PRDM1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
O75626

Purification
Affinity Purified

Immunogen
Peptide sequence around aa.124~128(D-T-V-P-K) derived from Human Blimp-1

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
B Lymphocyte Induced Maturation Protein 1 antibody, Beta interferon gene positive regulatory domain I binding factor antibody, Blimp 1 antibody, MGC118922 antibody, MGC118923 antibody, MGC118924 antibody, MGC118925 antibody, Positive Regulatory Domain I Binding Factor 1 antibody, PR domain containing 1 with ZNF domain isoform 2 antibody, PR domain zinc finger protein 1 antibody, PRDI BF1 antibody, PRDI binding factor 1 antibody

Application
ELISA,WB; Recommended dilution: WB:1:500-1:1000

 

VCU0006

User Guide & MSDS

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