This product was discontinued; sorry for the inconvenience. We recommend the following: Cat.# A63146.
BackgroundThe Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
DescriptionPhospho-PLK1-T210 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman
IsotypeIgG
Uniprot IDP53350
PurificationAffinity Purification
ImmunogenA synthetic phosphorylated peptide around T210 of human PLK1 (NP_005021.2).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesPLK1; PLK; STPK13; polo like kinase 1
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000