BackgroundHistone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
DescriptionPhospho Histone H1.4 (T17) Recombinant Monoclonal Antibody [3E1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDP10412
PurificationAffinity Chromatography
ImmunogenA synthesized peptide
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesHistone H1.4, Histone H1b, Histone H1s-4, HIST1H1E, H1F4
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:50-1:500, IF:1:30-1:200