BackgroundThe protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
DescriptionMAD2L1BP Monoclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ15013
PurificationAffinity Purified
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 175-274 of human MAD2L1BP (Q15013).
StorageStore at -20°C. Avoid freeze / thaw cycles.
Alternative NamesCMT2; MAD2L1BP
ApplicationIHC-P, IF/ICC, ELISA; Recommended dilution: IHC-P, 1:50 - 1:200; IF/ICC, 1:100 - 1:400; ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Cart (0)
