BackgroundPromotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1.
DescriptionFxn Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDO35943
PurificationProtein G purified
ImmunogenRecombinant Mouse Frataxin, mitochondrial protein (78-207AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesFrataxin, mitochondrial, Fxn, Frda, Fxn
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:5000