We recommend using an alternative version: p300 Polyclonal Antibody.
EP300 (E1A binding protein p300) is nuclear phosphoprotein which is conserved among a variety of mammalian species. It can act like a histone acetyltransferase to regulate transcription through chromatin remodeling and is important for cell proliferation and differentiation. EP300 binds specifically to phosphorylated CREB protein to mediate cAMP-gene regulation. It has also shown to function as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thereby is capable of stimulating hypoxia-induced genes such as VEGF. Abnormalities in this gene have been associated with Rubinstein-Taybi syndrome and epithelial cancer.
EP300 Monoclonal Antibody. Unconjugated. Raised in: Mouse.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recombinant Protein of human EP300
Store at 4℃. Avoid freeze / thaw cycles.
CREBBP/EP300 inhibitory protein 1 antibody, Cyclic AMP responsive enhancer binding protein antibody, E1A associated protein p300 antibody, EC 220.127.116.11 antibody, EP300: E1A binding protein p300 antibody, Histone acetyltransferase p300 antibody, p300 HAT antibody, RB and P300 binding protein EID 1 antibody, Retinoblastoma protein associated protein antibody, RSTS2 antibody
WB (1:500 - 1:2000)