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EP300 Monoclonal Antibody

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Western blot analysis of extracts of recombinant protein using EP300 Monoclonal Antibody.
Application: WB
Areas of Research: Histone Acetylation & Deacetylation
Clonality: Monoclonal
Conjugate: Unconjugated
Host: Mouse
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-4115-100100 µg $452.00  Discontinued
Availability: Discontinued 
Product Overview

We recommend using an alternative version: p300  Polyclonal Antibody.

 

Background
EP300 (E1A binding protein p300) is nuclear phosphoprotein which is conserved among a variety of mammalian species.  It can act like a histone acetyltransferase to regulate transcription through chromatin remodeling and is important for cell proliferation and differentiation. EP300 binds specifically to phosphorylated CREB protein to mediate cAMP-gene regulation. It has also shown to function as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thereby is capable of stimulating hypoxia-induced genes such as VEGF. Abnormalities in this gene have been associated with Rubinstein-Taybi syndrome and epithelial cancer.

Description
EP300 Monoclonal Antibody. Unconjugated. Raised in: Mouse.

Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human

Isotype
IgG

Uniprot ID
Q09472

Purification
Affinity purified

Immunogen
Recombinant Protein of human EP300

Storage
Store at 4℃. Avoid freeze / thaw cycles.

Alternative Names
CREBBP/EP300 inhibitory protein 1 antibody, Cyclic AMP responsive enhancer binding protein antibody, E1A associated protein p300 antibody, EC 2.3.1.48 antibody, EP300: E1A binding protein p300 antibody, Histone acetyltransferase p300 antibody, p300 HAT antibody, RB and P300 binding protein EID 1 antibody, Retinoblastoma protein associated protein antibody, RSTS2 antibody

Application
WB (1:500 - 1:2000)

SAC0002

User Guide & MSDS

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