BackgroundThe hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
DescriptionEGLN2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityMouse, Rat
IsotypeIgG
Uniprot IDQ96KS0
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 150-250 of human EGLN2 (NP_444274.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesEGLN2; EIT6; HIF-PH1; HIFPH1; HPH-1; HPH-3; PHD1; egl nine homolog 2
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000