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Development & Differentiation Antibodies

Development and differentiation includes processes by which a multicellular organism starts out from a single cell, a zygote, and gives rise to multiple cell types, forming different tissues and organs. Development comprises cell division, tissue and organ formation, body axis determination and cellular differentiation.

During development, cells must divide to form tissues and organs, while also they must differentiate into many diverse cell types with their distinctive features and functions. The totipotent zygote can give rise to all the cell types in the body and the placenta. As development progresses, cells potential to make up all cell types diminishes, and the embryonic stem cells become pluripotent, being able to give rise to all the cells of the body, except the placenta. The cells later differentiate into 3 germ layers: ectoderm, mesoderm and endoderm, and they conserve the ability to give rise to the cell types in their own lineage and not others. This is mostly under genetic control and different cell types start expressing different gene sets.

Differentiation is the process in which a cell develops its final cell type identity, and specific gene expression patterns allow the cell to synthesize RNA and protein specific for their structure and function. Not all cells in the body differentiate, some cells retain their ability to divide and produce multiple cell types. These include adult stem cells and cord blood stem cells, which are multipotent, as they have the ability to produce more than one cell type, but not all cell types. Hematopoietic stem cells are adult stem cells which give rise to the different cell types in blood. Stem cells undergo asymmetric cell division, producing two different daughter cells, one preserves the ability to self-renew and continues to be a stem cell, while the other becomes a differentiated cell.

An important group of genes controlling cellular differentiation during development are the HOX genes. They are not expressed in embryonic stem cells, but are expressed later by tissue stem cells in order to differentiate into their lineages and they are involved in determination of anterior-posterior body axis. Embryonic stem cells express transcription factors important for pluripotency, such as NANOG and OCT3/4 (POU5F1). Somatic cells can be reprogrammed to become induced pluripotent cells (iPS) by introducing transcription factors SOX2, KLF4, NANOG and OCT3/4.
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DMRT3 Polyclonal Antibody
DMRT3 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Developmental
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A70315-02020 µg $59.00 Add to Cart
A70315-05050 µg $249.00 Add to Cart
A70315-100100 µg $399.00 Add to Cart
Antibodies
DMRT3 Polyclonal Antibody, Biotin Conjugated
DMRT3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Developmental
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70318-05050 µg $249.00 Add to Cart
A70318-100100 µg $399.00 Add to Cart
Antibodies
DMRT3 Polyclonal Antibody, FITC Conjugated
DMRT3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Developmental
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70317-05050 µg $249.00 Add to Cart
A70317-100100 µg $399.00 Add to Cart
Antibodies
DMRT3 Polyclonal Antibody, HRP Conjugated
DMRT3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Developmental
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70316-05050 µg $249.00 Add to Cart
A70316-100100 µg $399.00 Add to Cart
Antibodies
DPPA3 Polyclonal Antibody
DPPA3 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68959-02020 µg $59.00 Add to Cart
A68959-05050 µg $249.00 Add to Cart
A68959-100100 µg $399.00 Add to Cart
Antibodies
DPPA3 Polyclonal Antibody, Biotin Conjugated
DPPA3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68962-05050 µg $249.00 Add to Cart
A68962-100100 µg $399.00 Add to Cart
Antibodies
DPPA3 Polyclonal Antibody, FITC Conjugated
DPPA3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68961-05050 µg $249.00 Add to Cart
A68961-100100 µg $399.00 Add to Cart
Antibodies
DPPA3 Polyclonal Antibody, HRP Conjugated
DPPA3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68960-05050 µg $249.00 Add to Cart
A68960-100100 µg $399.00 Add to Cart
Antibodies
DPPA4 Polyclonal Antibody
DPPA4 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58842-02020 µg $59.00 Add to Cart
A58842-05050 µg $256.00 Add to Cart
A58842-100100 µg $359.00 Add to Cart
Antibodies
DPPA4 Polyclonal Antibody, Biotin Conjugated
DPPA4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58843-05050 µg $256.00 Add to Cart
A58843-100100 µg $359.00 Add to Cart
Antibodies
DPPA4 Polyclonal Antibody, FITC Conjugated
DPPA4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58844-05050 µg $256.00 Add to Cart
A58844-100100 µg $359.00 Add to Cart
Antibodies
DPPA4 Polyclonal Antibody, HRP Conjugated
DPPA4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58845-05050 µg $256.00 Add to Cart
A58845-100100 µg $359.00 Add to Cart
Antibodies
DPPA5 Polyclonal Antibody
DPPA5 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69467-02020 µg $59.00 Add to Cart
A69467-05050 µg $249.00 Add to Cart
A69467-100100 µg $399.00 Add to Cart
Antibodies
DPPA5 Polyclonal Antibody, Biotin Conjugated
DPPA5 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69470-05050 µg $249.00 Add to Cart
A69470-100100 µg $399.00 Add to Cart
Antibodies
DPPA5 Polyclonal Antibody, FITC Conjugated
DPPA5 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69469-05050 µg $249.00 Add to Cart
A69469-100100 µg $399.00 Add to Cart
Antibodies
DPPA5 Polyclonal Antibody, HRP Conjugated
DPPA5 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69468-05050 µg $249.00 Add to Cart
A69468-100100 µg $399.00 Add to Cart
Antibodies
DPY19L1 Polyclonal Antibody
DPY19L1 Polyclonal Antibody

Application: ELISA, IF
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69811-02020 µg $59.00 Add to Cart
A69811-05050 µg $249.00 Add to Cart
A69811-100100 µg $399.00 Add to Cart
Antibodies
DPY19L1 Polyclonal Antibody, Biotin Conjugated
DPY19L1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69814-05050 µg $249.00 Add to Cart
A69814-100100 µg $399.00 Add to Cart
Antibodies
DPY19L1 Polyclonal Antibody, FITC Conjugated
DPY19L1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69813-05050 µg $249.00 Add to Cart
A69813-100100 µg $399.00 Add to Cart
Antibodies
DPY19L1 Polyclonal Antibody, HRP Conjugated
DPY19L1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69812-05050 µg $249.00 Add to Cart
A69812-100100 µg $399.00 Add to Cart
Antibodies
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