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Development & Differentiation Antibodies

Development and differentiation includes processes by which a multicellular organism starts out from a single cell, a zygote, and gives rise to multiple cell types, forming different tissues and organs. Development comprises cell division, tissue and organ formation, body axis determination and cellular differentiation.

During development, cells must divide to form tissues and organs, while also they must differentiate into many diverse cell types with their distinctive features and functions. The totipotent zygote can give rise to all the cell types in the body and the placenta. As development progresses, cells potential to make up all cell types diminishes, and the embryonic stem cells become pluripotent, being able to give rise to all the cells of the body, except the placenta. The cells later differentiate into 3 germ layers: ectoderm, mesoderm and endoderm, and they conserve the ability to give rise to the cell types in their own lineage and not others. This is mostly under genetic control and different cell types start expressing different gene sets.

Differentiation is the process in which a cell develops its final cell type identity, and specific gene expression patterns allow the cell to synthesize RNA and protein specific for their structure and function. Not all cells in the body differentiate, some cells retain their ability to divide and produce multiple cell types. These include adult stem cells and cord blood stem cells, which are multipotent, as they have the ability to produce more than one cell type, but not all cell types. Hematopoietic stem cells are adult stem cells which give rise to the different cell types in blood. Stem cells undergo asymmetric cell division, producing two different daughter cells, one preserves the ability to self-renew and continues to be a stem cell, while the other becomes a differentiated cell.

An important group of genes controlling cellular differentiation during development are the HOX genes. They are not expressed in embryonic stem cells, but are expressed later by tissue stem cells in order to differentiate into their lineages and they are involved in determination of anterior-posterior body axis. Embryonic stem cells express transcription factors important for pluripotency, such as NANOG and OCT3/4 (POU5F1). Somatic cells can be reprogrammed to become induced pluripotent cells (iPS) by introducing transcription factors SOX2, KLF4, NANOG and OCT3/4.
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EYA4 Polyclonal Antibody
EYA4 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69491-02020 µg $59.00 Add to Cart
A69491-05050 µg $249.00 Add to Cart
A69491-100100 µg $399.00 Add to Cart
Antibodies
EYA4 Polyclonal Antibody, Biotin Conjugated
EYA4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69494-05050 µg $249.00 Add to Cart
A69494-100100 µg $399.00 Add to Cart
Antibodies
EYA4 Polyclonal Antibody, FITC Conjugated
EYA4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69493-05050 µg $249.00 Add to Cart
A69493-100100 µg $399.00 Add to Cart
Antibodies
EYA4 Polyclonal Antibody, HRP Conjugated
EYA4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69492-05050 µg $249.00 Add to Cart
A69492-100100 µg $399.00 Add to Cart
Antibodies
FATE1 Polyclonal Antibody
FATE1 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation, Cell Growth
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A66582-02020 µg $59.00 Add to Cart
A66582-05050 µg $256.00 Add to Cart
A66582-100100 µg $359.00 Add to Cart
Antibodies
FATE1 Polyclonal Antibody, Biotin Conjugated
FATE1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66585-05050 µg $256.00 Add to Cart
A66585-100100 µg $359.00 Add to Cart
Antibodies
FATE1 Polyclonal Antibody, FITC Conjugated
FATE1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66584-05050 µg $256.00 Add to Cart
A66584-100100 µg $359.00 Add to Cart
Antibodies
FATE1 Polyclonal Antibody, HRP Conjugated
FATE1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A66583-05050 µg $256.00 Add to Cart
A66583-100100 µg $359.00 Add to Cart
Antibodies
FBLN2 Polyclonal Antibody
FBLN2 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69495-02020 µg $59.00 Add to Cart
A69495-05050 µg $249.00 Add to Cart
A69495-100100 µg $399.00 Add to Cart
Antibodies
FBLN2 Polyclonal Antibody, Biotin Conjugated
FBLN2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69498-05050 µg $249.00 Add to Cart
A69498-100100 µg $399.00 Add to Cart
Antibodies
FBLN2 Polyclonal Antibody, FITC Conjugated
FBLN2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69497-05050 µg $249.00 Add to Cart
A69497-100100 µg $399.00 Add to Cart
Antibodies
FBLN2 Polyclonal Antibody, HRP Conjugated
FBLN2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69496-05050 µg $249.00 Add to Cart
A69496-100100 µg $399.00 Add to Cart
Antibodies
FLII Polyclonal Antibody
FLII Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68843-02020 µg $59.00 Add to Cart
A68843-05050 µg $249.00 Add to Cart
A68843-100100 µg $399.00 Add to Cart
Antibodies
FLII Polyclonal Antibody, Biotin Conjugated
FLII Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68846-05050 µg $249.00 Add to Cart
A68846-100100 µg $399.00 Add to Cart
Antibodies
FLII Polyclonal Antibody, FITC Conjugated
FLII Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68845-05050 µg $249.00 Add to Cart
A68845-100100 µg $399.00 Add to Cart
Antibodies
FLII Polyclonal Antibody, HRP Conjugated
FLII Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68844-05050 µg $249.00 Add to Cart
A68844-100100 µg $399.00 Add to Cart
Antibodies
FNDC3B Polyclonal Antibody
FNDC3B Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A59146-02020 µg $59.00 Add to Cart
A59146-05050 µg $256.00 Add to Cart
A59146-100100 µg $359.00 Add to Cart
Antibodies
FNDC3B Polyclonal Antibody, Biotin Conjugated
FNDC3B Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A59147-05050 µg $256.00 Add to Cart
A59147-100100 µg $359.00 Add to Cart
Antibodies
FNDC3B Polyclonal Antibody, FITC Conjugated
FNDC3B Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A59148-05050 µg $256.00 Add to Cart
A59148-100100 µg $359.00 Add to Cart
Antibodies
FNDC3B Polyclonal Antibody, HRP Conjugated
FNDC3B Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A59149-05050 µg $256.00 Add to Cart
A59149-100100 µg $359.00 Add to Cart
Antibodies
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