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Introduction to Epigenetics

Development & Differentiation Antibodies

Development and differentiation includes processes by which a multicellular organism starts out from a single cell, a zygote, and gives rise to multiple cell types, forming different tissues and organs. Development comprises cell division, tissue and organ formation, body axis determination and cellular differentiation.

During development, cells must divide to form tissues and organs, while also they must differentiate into many diverse cell types with their distinctive features and functions. The totipotent zygote can give rise to all the cell types in the body and the placenta. As development progresses, cells potential to make up all cell types diminishes, and the embryonic stem cells become pluripotent, being able to give rise to all the cells of the body, except the placenta. The cells later differentiate into 3 germ layers: ectoderm, mesoderm and endoderm, and they conserve the ability to give rise to the cell types in their own lineage and not others. This is mostly under genetic control and different cell types start expressing different gene sets.

Differentiation is the process in which a cell develops its final cell type identity, and specific gene expression patterns allow the cell to synthesize RNA and protein specific for their structure and function. Not all cells in the body differentiate, some cells retain their ability to divide and produce multiple cell types. These include adult stem cells and cord blood stem cells, which are multipotent, as they have the ability to produce more than one cell type, but not all cell types. Hematopoietic stem cells are adult stem cells which give rise to the different cell types in blood. Stem cells undergo asymmetric cell division, producing two different daughter cells, one preserves the ability to self-renew and continues to be a stem cell, while the other becomes a differentiated cell.

An important group of genes controlling cellular differentiation during development are the HOX genes. They are not expressed in embryonic stem cells, but are expressed later by tissue stem cells in order to differentiate into their lineages and they are involved in determination of anterior-posterior body axis. Embryonic stem cells express transcription factors important for pluripotency, such as NANOG and OCT3/4 (POU5F1). Somatic cells can be reprogrammed to become induced pluripotent cells (iPS) by introducing transcription factors SOX2, KLF4, NANOG and OCT3/4.
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 424 products)
Image Description Cat. No. Size Price
ABHD14A Polyclonal Antibody
ABHD14A Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57942-02020 µgView
A57942-05050 µgView
A57942-100100 µgView
Antibodies
ABHD14A Polyclonal Antibody, Biotin Conjugated
ABHD14A Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57943-05050 µgView
A57943-100100 µgView
Antibodies
ABHD14A Polyclonal Antibody, FITC Conjugated
ABHD14A Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57944-05050 µgView
A57944-100100 µgView
Antibodies
ABHD14A Polyclonal Antibody, HRP Conjugated
ABHD14A Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57945-05050 µgView
A57945-100100 µgView
Antibodies
ABTB1 Polyclonal Antibody
ABTB1 Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57958-02020 µgView
A57958-05050 µgView
A57958-100100 µgView
Antibodies
ABTB1 Polyclonal Antibody, Biotin Conjugated
ABTB1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57959-05050 µgView
A57959-100100 µgView
Antibodies
ABTB1 Polyclonal Antibody, FITC Conjugated
ABTB1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57960-05050 µgView
A57960-100100 µgView
Antibodies
ABTB1 Polyclonal Antibody, HRP Conjugated
ABTB1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57961-05050 µgView
A57961-100100 µgView
Antibodies
AGRN Polyclonal Antibody
AGRN Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68451-02020 µgView
A68451-05050 µgView
A68451-100100 µgView
Antibodies
AGRN Polyclonal Antibody, Biotin Conjugated
AGRN Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68454-05050 µgView
A68454-100100 µgView
Antibodies
AGRN Polyclonal Antibody, FITC Conjugated
AGRN Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68453-05050 µgView
A68453-100100 µgView
Antibodies
AGRN Polyclonal Antibody, HRP Conjugated
AGRN Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68452-05050 µgView
A68452-100100 µgView
Antibodies
AMBN Polyclonal Antibody
AMBN Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A70287-02020 µgView
A70287-05050 µgView
A70287-100100 µgView
Antibodies
AMBN Polyclonal Antibody, Biotin Conjugated
AMBN Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70290-05050 µgView
A70290-100100 µgView
Antibodies
AMBN Polyclonal Antibody, FITC Conjugated
AMBN Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70289-05050 µgView
A70289-100100 µgView
Antibodies
AMBN Polyclonal Antibody, HRP Conjugated
AMBN Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70288-05050 µgView
A70288-100100 µgView
Antibodies
ANKRD7 Polyclonal Antibody
ANKRD7 Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A58078-02020 µgView
A58078-05050 µgView
A58078-100100 µgView
Antibodies
ANKRD7 Polyclonal Antibody, Biotin Conjugated
ANKRD7 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58079-05050 µgView
A58079-100100 µgView
Antibodies
ANKRD7 Polyclonal Antibody, FITC Conjugated
ANKRD7 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58080-05050 µgView
A58080-100100 µgView
Antibodies
ANKRD7 Polyclonal Antibody, HRP Conjugated
ANKRD7 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58081-05050 µgView
A58081-100100 µgView
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 424 products)
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