BackgroundMacromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
DescriptionCOL8A1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDP27658
Purification>95%, Protein G purified
ImmunogenRecombinant Human Collagen alpha-1(VIII) chain protein (572-744AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCollagen alpha-1(VIII) chain, Endothelial collagen, COL8A1, C3orf7
ApplicationELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200