BackgroundInhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
DescriptionCCL21 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDO00585
Purification>95%, Protein G purified
ImmunogenRecombinant Human C-C motif chemokine 21 protein (24-134AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative Names6Ckine Beta-chemokine exodus-2 Secondary lymphoid-tissue chemokine CCL21 SCYA21 UNQ784/PRO1600
ApplicationELISA, IHC; Recommended dilution: IHC:1:200-1:500