BackgroundThis gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
DescriptionBDNF Recombinant Monoclonal Antibody [1A1]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman, Mouse
IsotypeRabbit IgG
Uniprot IDP23560
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human BDNF
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesBrain-derived neurotrophic factor (BDNF) (Abrineurin), BDNF
ApplicationELISA, WB; Recommended dilution: WB:1:500-1:2000