BackgroundSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
DescriptionBcl2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityMouse
IsotypeIgG
Uniprot IDP10417
PurificationProtein G purified
ImmunogenRecombinant Mouse Apoptosis regulator Bcl-2 protein (5-205AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesBcl2, Bcl-2
ApplicationELISA, IHC; Recommended dilution: IHC:1:10-1:100
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