The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet.
AKR1D1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human AKR1D1 (NP_005980.1).
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
AKR1D1; 3o5bred; CBAS2; SRD5B1; 3-oxo-5-beta-steroid 4-dehydrogenase
WB; Recommended dilution: WB 1:500 - 1:2000