BackgroundMetallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
DescriptionAGBL2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Formulation0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ5U5Z8
PurificationProtein G purified
ImmunogenRecombinant Human Cytosolic carboxypeptidase 2 protein (10-270AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesCytosolic carboxypeptidase 2 (EC:3.4.17.-), AGBL2, CCP2, ATP/GTP-binding protein-like 2
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200