Background Myc gene encodes for a transcription factor that is believed to regulate expression of 15% of all genes through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferases (HATs). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. This c-Myc antibody detects endogenous levels of total c-Myc protein and is also for detection of Myc-tagged fusion protein.
DescriptionRabbit polyclonal antibody to c-Myc, HRP conjugated
PurificationAffinity purified
SpecificityHuman
IsotypeIgG
ImmunogenThis antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the residues of c-myc.
FormulationLiguid. 1*TBS (pH7.4), 0.5% BSA, 25% Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at 4°C after thawing. Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Alternative NamesMYC, BHLHE39,bHLHe39, Class E basic helix-loop-helix protein 39, Transcription factor p64, Proto-oncogene c-Myc, Myc proto-oncogene protein, C-myc HRP Conjugated, Anti c-Myc Polyclonal Tag HRP Conjugated
ApplicationWB: 1:1,000-1:2,000
JHB0002
Fig. 1. Western blot analysis on myc-tagged recombinant protein using c-Myc Polyclonal Tag Antibody, HRP Conjugated.