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DNMT ELISA Easy Kit
Modified Histone Proteins

Modified Histone Proteins

These recombinant histone proteins have various site-specific and degree-specific modifications including methylation, demethylation, acetylation, deacetylation, phosphorylation, and sumoylation. Modified histone proteins play a role in a wide variety of processes including regulating gene expression. Specifically, they are implicated in diseases as a result of disrupted gene expression.
Histone Methylation Proteins
Histone methyltransferase (HMT) proteins are involved in the post-translational modification called histone methylation which causes transcription repression or activation, depending on the target sites. Protein arginine methyltransferases (PRMTs) catalyze the methylation of arginine residues and histone methyltransferases (HMTs) catalyze the methylation of lysine residues.

Histone Demethylation Proteins
Histone demethylase (HDM) proteins are involved in the post-translational modification called histone demethylation which entails the removal of methyl groups in modified histone proteins. Protein arginine demethylase (PRDM) catalyzes the removal of methyl groups from arginine residues while lysine demethylase (KDM) catalyzes the removal from lysine demethylase (KDM).

Histone Acetylation Proteins
Histone acetyltransferase (HATs) proteins are involved in histone acetylation, or the addition of an acetyl group to lysine residues in the N-terminal tail and on the surface of the nucelosome core of histone proteins. They play a role in adjusting chromatin structure, leading to increased or decreased gene transcription levels. In general, histone acetylation is associated with increased gene expression.

Histone Deacetylation Proteins
Histone deacetylase (HDAC) proteins are involved in histone deacetylation, or the removal of an acetyl group to lysine residues in the N-terminal tail and on the surface of the nucelosome core of histone proteins. They play a role in adjusting chromatin structure, leading to increased or decreased gene transcription levels. In general, histone deacetylation is linked to transcriptional repression.

Histone Phosphorylation Proteins
Histone phosphorylation has been shown to impact an assortment of processes such as chromosome condensation, transcription, DNA repair, and apoptosis. An increase in phosphorylation is linked to gene activation and cell growth. Investigating the changes in histone phosphorylation levels using histone phosphorylation proteins such as Aurora Kinase A (AURKA) and MSK1 will aid researchers in understanding diseases and their pathological processes and can advance the creation of protein ki...

Histone Sumoylation Proteins
These histone proteins are involved in sumoylation, a post-translational modification directed by an enzymatic cascade in which Small Ubiquitin-like Modifier (SUMO) proteins are attached to or detached from other proteins to change their function in cells. Detection of SUMO conjugation or protein Sumoylation can help researchers understand how this modification plays a role in regulating nuclear protein activity and in certain cellular processes, such as transcriptional regulation, apo...

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JARID1A Protein
JARID1A Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24020-120 µg $524.00 Add to Cart
Proteins & Enzymes
JARID1C Protein
JARID1C Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24021-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2A Protein
JMJD2A Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24022-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2B Protein
JMJD2B Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24023-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2C Protein
JMJD2C Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24024-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD2D Protein
JMJD2D Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24025-120 µg $524.00 Add to Cart
Proteins & Enzymes
JMJD3 Protein
JMJD3 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24026-120 µg $524.00 Add to Cart
Proteins & Enzymes
LSD1 Protein
LSD1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24027-150 µg $524.00 Add to Cart
Proteins & Enzymes
Pcaf Protein
Pcaf Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E29000-150 µg $689.00 Add to Cart
Proteins & Enzymes
PRMT4 Protein
PRMT4 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24033-120 µg $524.00 Add to Cart
Proteins & Enzymes
PRMT5 Protein
PRMT5 Protein

Expressed In: sf9 Cells
Protein Species: Human
Research Area: Histone Methylation
E24034-120 µg $524.00 Add to Cart
Proteins & Enzymes
SAP18 Protein
SAP18 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E20000-120 µg $300.00 Add to Cart
Proteins & Enzymes
SET7 Protein
SET7 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E23000-150 µg $411.00 Add to Cart
Proteins & Enzymes
SET8 Protein
SET8 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Methylation
E24035-150 µg $524.00 Add to Cart
Proteins & Enzymes
Sirtuin1 Protein
Sirtuin1 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24015-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin2 Protein
Sirtuin2 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24016-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin3 Protein
Sirtuin3 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24017-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin4 Protein
Sirtuin4 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24018-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin5 Protein
Sirtuin5 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24019-1100 µg $522.00 Add to Cart
Proteins & Enzymes
Sirtuin6 Protein
Sirtuin6 Protein

Expressed In: E. Coli
Protein Species: Human
Research Area: Histone Acetylation
E24013-1100 µg $522.00 Add to Cart
Proteins & Enzymes
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