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MLN8237 (Alisertib)

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Application: EnzymeInhibition
Molecular Weight: >500
Research Area: Histone Phosphorylation
Solubility: DMSO, Ethanol, Water
100% Guarantee: 6 months
Catalog No.SizePriceQty
M76000-15 mg $261.00  Discontinued
Availability: Discontinued 
Product Overview

Alternative Names
Alisertib

Description
MLN8237 is a selective Aurora kinase A inhibitor with median IC50 of 61 nM. MLN8237 (Alisertib) is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the Aurora A kinase (serine/threonine protein kinase) with potential antineoplastic activity. MLN8237 (Alisertib) binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. 

CAS Number
1028486-01-2

Chemical Formula
C27H20ClFN4O4

Molecular Weight
518.92

Size
5 mg

Purity
99.27%

Solubility
DMSO ≥44mg/mL Water <1mg/mL Ethanol <1mg/mL

Storage Temp
-20°C

User Guide & MSDS

[User Guide]*
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