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Introduction to Epigenetics
Immunology & Inflammation Antibodies

Immunology & Inflammation Antibodies

cell mediated immune responseImmunology and inflammation antibodies are a broad set of antibodies ideal for investigating the complex immune system, including cell marker and receptor antibodies, cytokine antibodies, and other immunology antibodies.

Epigenetic mechanisms have been closely involved in inflammatory pathways and using antibodies that recognize specific antigens related to the immune system and inflammation offers researchers insight into the potential pathological epigenetic modifications and immunological and inflammatory complications linked to a multitude of diseases.

Immunology covers a wide range of processes including adaptive immunity, innate immunity, and the regulation of the immune system in the naïve state as well as active state when fighting disease, infection, and disorders that may be caused by agents such as viruses, fungi, bacteria, and parasites. Additionally, immunology and inflammation antibodies can be helpful in detecting biomarkers for disease, especially cancer.

Cell marker and receptor antibodies help investigate cell surface markers of immune cells, which also may act as cell surface receptors or ligands, playing a role in signaling, cell adhesion, and antigen presentation. For example, the beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and is involved in the presentation of peptide antigens to the immune system. In addition, C-C chemokine receptor type 4 (CCR4) can act as a chemoattractant homing receptor on circulating memory lymphocytes as well as a coreceptor for select primary HIV-2 isolates, potentially mediating hippocampal-neuron survival.

Cytokine antibodies are central to communicating with and altering the actions of other immune cells. Secreted by most immune cells – including T-cells, B-cells, monoctyes, NK cells, macrophages, and T-helper cells (TH cells) – cytokines can be pro- or anti-inflammatory. Popular cytokines involved in inflammation include tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), and interleukin 1 beta (IL-1 beta). Other well-known anti-inflammatory cytokines involved in stifling inflammatory responses include interleukin 4 (IL-4), interleukin 10 (IL-10), interleukin 11 (IL-11), and interleukin 13 (IL-13).

Other immunology antibodies can aid in the identification of cancer biomarkers, such as tumor antigens produced by cancer cells, which incite a response by the immune system in order to target the invading cancer cells. Other immunology antibodies are targeted against antigens such as allergens, which may or may not provoke an immune response in different individuals.
Cell Marker & Receptor Antibodies
Immune cells possess cell surface markers designated as CD (cluster of differentiation) molecules. These cell surface proteins serve as cell surface markers for identification of the diverse immune cell types, but also have roles as cell surface receptors or ligands involved in antigen presentation, signaling and cell adhesion. There are more than three hundred cell surface markers identified in human immune cells, as well as other nonimmune cells, such as endothelial and epithelial cells, which often express these markers.

Cytokine Antibodies
Cytokines are small proteins secreted by immune cells to communicate and alter the actions of other immune cells. They can be pro-inflammatory or anti-inflammatory, thus promoting or inhibiting the proliferation and functions of other immune cells. Cytokines are often called by other names depending mostly on the cell that produces them or on their biological functions. Lymphokines are produced by lymphocytes, monokines are released by monocytes, and interleukins are produced in one leukocyte but act on other leukocytes. Chemokines have chemotactic roles, which include the activation and migration of leukocytes. Different immune cells can secrete the same cytokine, while the same cytokine can act on several immune cells. Cytokines can act in an autocrine, paracrine or endocrine manner, and often the secretion of one cytokine promotes secretion of additional cytokines in the other immune cells.

Other Immunology Antibodies
Other proteins besides cell surface immune markers and cytokines also participate in immune responses. For instance, the complement system is involved in the defense against infections and is mediated by a group of plasma proteins that interact with each other on the surface of a pathogen. It complements the defense responses mediated by an antibody, but can also act in the absence of antibody-mediated reactions. Three pathways can cause complement activation, the classical pathway, the lectin pathway and the alternative pathway. Complement activation leads to opsonization of pathogens, recruitment of inflammatory cells, and direct killing of pathogens.

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Arachin Ahy-3 Polyclonal Antibody
Arachin Ahy-3 Polyclonal Antibody

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Peanut
Trial Size Available: Yes
A56270-02020 µg $59.00 Add to Cart
A56270-05050 µg $256.00 Add to Cart
A56270-100100 µg $359.00 Add to Cart
Antibodies
Arachin Ahy-3 Polyclonal Antibody, Biotin Conjugated
Arachin Ahy-3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Peanut
A56273-05050 µg $256.00 Add to Cart
A56273-100100 µg $359.00 Add to Cart
Antibodies
Arachin Ahy-3 Polyclonal Antibody, FITC Conjugated
Arachin Ahy-3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Peanut
A56272-05050 µg $256.00 Add to Cart
A56272-100100 µg $359.00 Add to Cart
Antibodies
Arachin Ahy-3 Polyclonal Antibody, HRP Conjugated
Arachin Ahy-3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Peanut
A56271-05050 µg $256.00 Add to Cart
A56271-100100 µg $359.00 Add to Cart
Antibodies
B2M Polyclonal Antibody
B2M Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A57870-02020 µg $59.00 Add to Cart
A57870-05050 µg $256.00 Add to Cart
A57870-100100 µg $359.00 Add to Cart
Antibodies
BAGE3 Polyclonal Antibody
BAGE3 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A65774-02020 µg $59.00 Add to Cart
A65774-05050 µg $256.00 Add to Cart
A65774-100100 µg $359.00 Add to Cart
Antibodies
BAGE3 Polyclonal Antibody, Biotin Conjugated
BAGE3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65777-05050 µg $256.00 Add to Cart
A65777-100100 µg $359.00 Add to Cart
Antibodies
BAGE3 Polyclonal Antibody, FITC Conjugated
BAGE3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65776-05050 µg $256.00 Add to Cart
A65776-100100 µg $359.00 Add to Cart
Antibodies
BAGE3 Polyclonal Antibody, HRP Conjugated
BAGE3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A65775-05050 µg $256.00 Add to Cart
A65775-100100 µg $359.00 Add to Cart
Antibodies
bar Polyclonal Antibody
bar Polyclonal Antibody

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Streptomyces hygroscopicus
Trial Size Available: Yes
A54543-02020 µg $59.00 Add to Cart
A54543-05050 µg $256.00 Add to Cart
A54543-100100 µg $359.00 Add to Cart
Antibodies
bar Polyclonal Antibody, Biotin Conjugated
bar Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Streptomyces hygroscopicus
A54540-05050 µg $256.00 Add to Cart
A54540-100100 µg $359.00 Add to Cart
Antibodies
bar Polyclonal Antibody, FITC Conjugated
bar Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Streptomyces hygroscopicus
A54541-05050 µg $256.00 Add to Cart
A54541-100100 µg $359.00 Add to Cart
Antibodies
bar Polyclonal Antibody, HRP Conjugated
bar Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Streptomyces hygroscopicus
A54542-05050 µg $256.00 Add to Cart
A54542-100100 µg $359.00 Add to Cart
Antibodies
Beta-2-Microglobulin Polyclonal Antibody, Biotin Conjugated
Beta-2-Microglobulin Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57873-05050 µg $256.00 Add to Cart
A57873-100100 µg $359.00 Add to Cart
Antibodies
Beta-2-Microglobulin Polyclonal Antibody, FITC Conjugated
Beta-2-Microglobulin Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57872-05050 µg $256.00 Add to Cart
A57872-100100 µg $359.00 Add to Cart
Antibodies
Beta-2-Microglobulin Polyclonal Antibody, HRP Conjugated
Beta-2-Microglobulin Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57871-05050 µg $256.00 Add to Cart
A57871-100100 µg $359.00 Add to Cart
Antibodies
bla Polyclonal Antibody
bla Polyclonal Antibody

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
Trial Size Available: Yes
A56378-02020 µg $59.00 Add to Cart
A56378-05050 µg $256.00 Add to Cart
A56378-100100 µg $359.00 Add to Cart
Antibodies
bla Polyclonal Antibody, Biotin Conjugated
bla Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A56381-05050 µg $256.00 Add to Cart
A56381-100100 µg $359.00 Add to Cart
Antibodies
bla Polyclonal Antibody, FITC Conjugated
bla Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A56380-05050 µg $256.00 Add to Cart
A56380-100100 µg $359.00 Add to Cart
Antibodies
bla Polyclonal Antibody, HRP Conjugated
bla Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Immunology & Inflammation
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A56379-05050 µg $256.00 Add to Cart
A56379-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 61 to 80 (of 2350 products)
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