HSP60/HSPD1 Monoclonal Antibody

Background
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Description
HSP60/HSPD1 Monoclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.

Specificity
Human, Mouse, Rat, Wheat

Isotype
IgG

Uniprot ID
P10809

Purification
Affinity Purified

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human HSP60/HSPD1 (P10809).

Storage
Store at -20°C. Avoid freeze / thaw cycles.

Alternative Names
HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60; HSP60/HSPD1

Application
WB, IHC-P, IF/ICC, ELISA; Recommended dilution: WB, 1:5000 - 1:30000; IHC-P, 1:2000 - 1:8000; IF/ICC, 1:100 - 1:1000; ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.