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Phosphatase Antibodies

Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Two important phosphatases include the serine/threonine protein phosphatase 2A (PP2A) and phosphatase and tensin homolog (PTEN). PP2A is a key phosphatase as it catalyzes dephosphorylation of many proteins, but also dephosphorylates the main protein kinases responsible for activation of major signaling pathways, including AKT, ERK MAP kinase and Protein kinase C (PKC) family members. PTEN dephosphorylates proteins, as well as the phospholipid phosphatidylinositol (3,4,5)-trisphosphate (PIP3), which induces inhibition of signaling by AKT, a critical pathway involved in cellular growth and proliferation. PTEN is a tumor suppressor frequently mutated and involved in the pathogenesis and progression of several cancers.

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

  • No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
  • 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
  • Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
  • Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.

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PPTC7 Polyclonal Antibody
PPTC7 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A66530-02020 µg $99.00 Add to Cart
A66530-05050 µg $256.00 Add to Cart
A66530-100100 µg $359.00 Add to Cart
Antibodies
PPTC7 Polyclonal Antibody, Biotin Conjugated
PPTC7 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A66533-05050 µg $256.00 Add to Cart
A66533-100100 µg $359.00 Add to Cart
Antibodies
PPTC7 Polyclonal Antibody, FITC Conjugated
PPTC7 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A66532-05050 µg $256.00 Add to Cart
A66532-100100 µg $359.00 Add to Cart
Antibodies
PPTC7 Polyclonal Antibody, HRP Conjugated
PPTC7 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A66531-05050 µg $256.00 Add to Cart
A66531-100100 µg $359.00 Add to Cart
Antibodies
Prostatic Acid Phosphatase Polyclonal Antibody, FITC Conjugated
Prostatic Acid Phosphatase Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A57765-05050 µg $256.00 Add to Cart
A57765-100100 µg $359.00 Add to Cart
Antibodies
Prostatic Acid Phosphatase Polyclonal Antibody, HRP Conjugated
Prostatic Acid Phosphatase Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A57764-05050 µg $256.00 Add to Cart
A57764-100100 µg $359.00 Add to Cart
Antibodies
PTEN Polyclonal Antibody
PTEN Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A52436-02020 µg $99.00 Add to Cart
A52436-05050 µg $256.00 Add to Cart
A52436-100100 µg $359.00 Add to Cart
Antibodies
PTEN Polyclonal Antibody, Biotin Conjugated
PTEN Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52433-05050 µg $256.00 Add to Cart
A52433-100100 µg $359.00 Add to Cart
Antibodies
PTEN Polyclonal Antibody, FITC Conjugated
PTEN Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52434-05050 µg $256.00 Add to Cart
A52434-100100 µg $359.00 Add to Cart
Antibodies
PTEN Polyclonal Antibody, HRP Conjugated
PTEN Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A52435-05050 µg $256.00 Add to Cart
A52435-100100 µg $359.00 Add to Cart
Antibodies
PTP4A1 Polyclonal Antibody
PTP4A1 Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A66810-02020 µg $99.00 Add to Cart
A66810-05050 µg $256.00 Add to Cart
A66810-100100 µg $359.00 Add to Cart
Antibodies
PTP4A1 Polyclonal Antibody, Biotin Conjugated
PTP4A1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A66813-05050 µg $256.00 Add to Cart
A66813-100100 µg $359.00 Add to Cart
Antibodies
PTP4A1 Polyclonal Antibody, FITC Conjugated
PTP4A1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A66812-05050 µg $256.00 Add to Cart
A66812-100100 µg $359.00 Add to Cart
Antibodies
PTP4A1 Polyclonal Antibody, HRP Conjugated
PTP4A1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Cycle, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A66811-05050 µg $256.00 Add to Cart
A66811-100100 µg $359.00 Add to Cart
Antibodies
PTP4A2 Polyclonal Antibody
PTP4A2 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69843-02020 µg $99.00 Add to Cart
A69843-05050 µg $249.00 Add to Cart
A69843-100100 µg $399.00 Add to Cart
Antibodies
PTP4A2 Polyclonal Antibody, Biotin Conjugated
PTP4A2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69846-05050 µg $249.00 Add to Cart
A69846-100100 µg $399.00 Add to Cart
Antibodies
PTP4A2 Polyclonal Antibody, FITC Conjugated
PTP4A2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69845-05050 µg $249.00 Add to Cart
A69845-100100 µg $399.00 Add to Cart
Antibodies
PTP4A2 Polyclonal Antibody, HRP Conjugated
PTP4A2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69844-05050 µg $249.00 Add to Cart
A69844-100100 µg $399.00 Add to Cart
Antibodies
PTPMT1 Polyclonal Antibody
PTPMT1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Rat
Trial Size Available: Yes
A55958-02020 µg $99.00 Add to Cart
A55958-05050 µg $256.00 Add to Cart
A55958-100100 µg $359.00 Add to Cart
Antibodies
PTPMT1 Polyclonal Antibody, Biotin Conjugated
PTPMT1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Metabolism, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55961-05050 µg $256.00 Add to Cart
A55961-100100 µg $359.00 Add to Cart
Antibodies
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