The Methylamp™ Universal Methylated DNA Preparation Kit provides a tool for generating methylated DNA at CpG sites as the methylation-positive control used for methylation studies. The kit uses DNA from various sources including genomic DNA, plasmid DNA and oligonucleotides. It includes all the components needed for generating and purifying methylated DNA and is sufficient for methylating 40 µg of DNA. This kit can be used with the Methylamp™ DNA Modification Kit series. It can also be used with other DNA modification or methylation kits.
Fig. 1. Workflow of the Methylamp™ Universal Methylated DNA Preparation Kit.
Wang W et. al. (July 2015). 5-Azacitidine induces demethylation of PTPL1 and inhibits growth in non-Hodgkin lymphoma. Int J Mol Med.