GAPDH Monoclonal Tag Antibody [4G5]

Description
GAPDH Tag Antibody recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism.GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.

Antibody Type
Monoclonal Antibody

Purification
Purified IgG - liquid

Immunogen
Human cardiac muscle GADPH

Isotype
IgG1

Size
200 µg

Formulation
Phosphate buffered saline. 0.09% Sodium Azide (NaN3) 

Specificity
Bovine; Cat; Dog; Fish; Goat; Mouse; Pig; Rabbit; Rat

Storage
Store at +4ºC or at -20ºC if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.

Handling Recommendations
Should this product contain a precipitate we recommend microcentrifugation before use. For maximum recovery of the products, centrifuge the vial prior to opening the cap.

Applications & Suggested Dilutions
ELISA; Immunofluorescence; Immunohistology - Frozen; Immunoprecipitation; Western Blotting