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DR2313

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Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Phosphorylation
Solubility: Water
100% Guarantee: 6 months
Catalog No.SizePriceQty
M75002-110 mg $140.00  Discontinued
Availability: Discontinued 
Product Overview

Alternative Names
2-Methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]pyrimidine-4-one

Description
PARP Inhibitor XI, DR2313 is a water soluble and brain-permeable pyrimidinone compound that functions as a Poly(ADP-ribose) polymerase inhibitor. Poly(ADP-ribose) polymerases, known as PARP, function by triggering DNA repair mechanisms and activating apoptosis in damaged cells. Studies show that DR2313 is a NAD+ utilizing enzyme which competitively inhibits Poly(ADP-ribose) polymerases but does not display selectivity among PARP-1 and PARP-2. In addition, in vitro studies of cerebral ischemia exhibiting an overactivation of PARP can be reduced by introducing DR2313

CAS Number
284028-90-6

Chemical Formula
C8H10N2OS

Molecular Weight
182.2

Size
10 mg

Purity

>98%

Solubility
H2O

Storage Temp
-20°C

User Guide & MSDS

[User Guide]*
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