Cell Marker & Receptor Antibodies

Immune cells possess cell surface markers designated as CD (cluster of differentiation) molecules. These cell surface proteins serve as cell surface markers for identification of the diverse immune cell types, but also have roles as cell surface receptors or ligands involved in antigen presentation, signaling and cell adhesion. There are more than three hundred cell surface markers identified in human immune cells, as well as other nonimmune cells, such as endothelial and epithelial cells, which often express these markers.

CD3, CD4 and CD8 are T-cell markers, while CD19 and CD20 are markers of B-cells. T-helper cells are generally characterized by presence of CD4 glycoprotein, and are referred to as CD4+ cells, whereas cytotoxic T-cells or killer T-cells generally express CD8 at the cell surface and are called CD8+ cells. Dendritic cells, macrophages, platelets and other hematopoietic cells express a variety of these receptors. Whether a T-cell is in the naïve or activated state can also be discriminated by presence of specific cell surface markers. Labeling cells with antibodies specific for cell surface markers is commonly used in flow cytometry to distinguish and isolate distinct immune cell populations.

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

• No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
• 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
• Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
• Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.