LSD1 is a nuclear homolog of amine oxidases and functions as a histone demethylaseand transcriptional corepressor. LSD1specifically demethylates histone H3 lysine 4,which is linked to active transcription. LSD1 is highly conserved between organismsranging from the fission yeast saccharomyces pombe to humans. LSD1 associates withother histone-modifying enzymes such as histone deacetylases and methyltransferases. In concert with transcription repression, loss of LSD1 function leads to derepression ofgenes regulated by Co-REST, a protein involved in gene silencing and a member ofthe LSD1.
LSD1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
Liquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
Protein G purified
Recombinant Human Lysine-specific histone demethylase 1A protein (100-150AA)
Shipped at 4°C. Store at -20°C or -80°C. Avoid repeated freeze.
Amine oxidase flavin containing domain 2 antibody, AOF 2 antibody, BHC110 antibody, BRAF35 HDAC complex protein BHC110 antibody, FAD binding protein BRAF35 HDAC complex 110 kDa subunit antibody, Flavin containing amine oxidase domain containing protein 2 antibody, KDM 1 antibody, KIAA0601 antibody, LSD 1 antibody, Lysine (K) specific demethylase 1A antibody, Lysine specific histone demethylase 1 antibody
ELISA, WB, IHC, IF; Recommended dilution: IHC: 1:20-1:200, IF: 1:50-1:200