SUV39H2 Polyclonal Antibody

Background
SUV39H2 encodes a H3 HMTase that shares 59% identity with SUV39H1, but which differs by the presence of a highly basic N terminus. SUV39H2 is also responsible for creating HP1 binding sites in heterochromatin by methylation of histone H3-Lys9. Moreover, SUV39H2 specifically accumulates with chromatin of the sex chromosomes (XYbody), which undergo transcriptional silencing during the first meiotic prophas.

Description
SUV39H2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
Q9H5I1

Purification
Affinity Purification

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 141-350 of human SUV39H2 (NP_001180354.1).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
FLJ23414 antibody, H3 K9 HMTase 2 antibody, Histone H3 K9 methyltransferase 2 antibody, Histone lysine N methyltransferase H3 lysine 9 specific 2 antibody, Histone lysine N methyltransferase SUV39H2 antibody, KMT1B antibody, Lysine N methyltransferase 1B antibody, Suppressor of variegation 3 9 homolog 2 (Drosophila) antibody, Su(var)3 9 Drosophila homolog of 2 antibody, Suppressor of variegation 3 9 homolog 2 antibody, Suv39h2 antibody, SUV92_HUMAN antibody

Application
WB, IF, ChIP; Recommended dilution: WB 1:500 - 1:2000, IF 1:50 - 1:200, ChIP 1:20 - 1:100