*10% Off Bisulfite Conversion, MeDIP, MSP/MS-PCR and NGS Kits! Use Code E2411SSA: Ends 11/30/2024.

Extraction

Global DNA Modification ELISAs

5-mC

Enzyme Activity/Inhibition ELISAs

DNMT

TET

» Comprehensive Solutions for DNA Modification Analysis

Site-Specific & Genome-Wide DNA Methylation Assays

▶ DNA Bisulfite Conversion
Get reliable DNA methylation data with EpigenTek’s easy-to-use bisulfite conversion kits. The BisulFlash DNA Modification Kit delivers pure, bisulfite-modified DNA in just 30 minutes. For simultaneous 5mC and 5hmC detection by PCR, try our unique BisulPlus Loci 5mC & 5hmC Detection PCR Kit. Our proprietary formula protects against DNA loss, ensuring high recovery efficiency for next-gen sequencing and pyrosequencing.

▶ Methylated DNA Immunoprecipitation
If you’re seeking a quick, efficient way to identify cytosine modifications in DNA, EpigenTek’s MeDIP and hMeDIP kits are ideal. Our kits use high-affinity antibodies specific to 5mC or 5hmC, ensuring accurate enrichment of methylated or hydroxymethylated DNA in a convenient 96-well format. The captured DNA is ready for PCR, microarray, or sequencing analysis.

▶ Methylated DNA Amplification
Discover the advantages of Methylated DNA Amplification with our advanced techniques, including Methylation-specific PCR (MSP) using the Methylamp MS-qPCR Fast Kit and EpiQuik Quantitative PCR Fast Kit. These powerful tools offer critical insights into gene regulation and the influence of methylation on health and disease, helping you drive your research forward.

▶ Next Generation Sequencing
Transform your DNA analysis with Next-Generation Sequencing (NGS) solutions from EpigenTek. Our affordable options include comprehensive kits designed to construct high-quality DNA libraries from low quantities or challenging samples. For example, the EpiNext™ RRBS Library Fast Kit enables rapid preparation of reduced representation bisulfite sequencing (RRBS) DNA libraries, ensuring high coverage from minimal starting material.

*10% Off Offer: Applies only to products in the above categories (any size) with code E2411SSA. Orders must include the code to receive the discount. No retroactive discounts allowed. Offer valid for U.S. customers only. Not available to distributors or resellers. Cannot be combined with other offers. Expires November 30, 2024.

Featured Kits

DNA Bisulfite Conversion
Click image to see more details	BisulFlash DNA Modification Kit For lightning-fast bisulfite treatment of DNA for methylation-specific PCR analysis in just 30 minutes Fast: The entire procedure is as short as 30 minutes without any reagent setup time Highly Efficient: Completely convert unmethylated cytosine into uracil: modified DNA > 99.9% DNA Protection: Protect against DNA degradation of which more than 90% of DNA loss can be prevented, allowing for greater recovery High Sensitivity: Start with the lowest amount of input DNA for modification -- only 0.2 ng or just 50 cells Catalog #: P-1026
Click image to see more details	BisulPlus Loci 5mC & 5hmC Detection PCR Kit Reliably detects 5hmC and 5mC simultaneously by PCR using a tiny amount of input DNA Simultaneous Reading: DNA treatment is simultaneously prepared for both 5hmC and 5mC, allowing for parallel identification in a loci- or gene-specific manner by qPCR Fast: The enitire procedure from DNA bisulfite treatment to PCR products can be completed within 5 hours Highly Efficient: Completely converts C into uracil (>99%) and 5mC to thymine (>95%) High Specificity: 5hmC is discriminated from C and 5mC as well as from other modified cytosines 5fC and 5caCr Flexible: Perform 24 reactions for 5hmC and 24 reactions for 5mC analysis simultaneously, or perform 48 reactions for just 5mC Catalog #: P-1067
Methylated DNA Immunoprecipitation
Click image to see more details	Methylamp Methylated DNA Capture (MeDIP) Kit For enrichment and capture of methylated DNA fragments for microarray, PCR, or NGS applications Fast: The entire procedure can be finished within 3 hours Highly Efficient: Enrichment of methylated DNA: > 98% Convenient: Contains all reagents required to enrich and capture methylated DNA fragments and compatible with all DNA amplification-based approaches Flexible: Strip-well microplate format makes the assay flexible: manual or high throughput Catalog #: P-1015
Click image to see more details	EpiQuik Hydroxymethylated DNA Immunoprecipitation (hMeDIP) Kit For antibody-based capture of hydroxymethylated DNA fragments for microarray, PCR, or NGS applications Fast: Total protocol time is less than 3 hours Highly Efficient: Enrichment ratio of positive/negative control > 100 Convenient: Contains all reagents required to enrich and capture methylated DNA fragments and compatible various downstream analysis workflows including hMeDIP-PCR and hMeDIP-chip Flexible: Strip-well microplate format makes the assay flexible: manual or high throughput Catalog #: P-1038
Methylated DNA Amplification
Click image to see more details	Methylamp MS-qPCR Fast Kit Perform fast, specific, sensitive and reproducible methylation-specific quantitative PCR Fast: Can be finished within 70 minutes Highly Efficient: Abundant yields due to high amplification efficiency Convenient: Master mix format allows easy reaction setup Flexible: Can be used with any block-based real-time PCR instrument Catalog #: P-1028
Click image to see more details	EpiQuik Quantitative PCR Fast Kit For quantitative real time PCR analysis of ChIP, hmeDIP, meDIP, and meRIP DNA Fast: Can be finished within 70 minutes Highly Efficient: Abundant yields due to high amplification efficiency Convenient: Master mix format allows easy reaction setup Flexible: Can be used with any block-based real-time PCR instrument Catalog #: P-1029
Next Generation Sequencing
Click image to see more details	EpiNext RRBS Library Fast Kit Prepare reduced representative bisulfite sequencing (RRBS) DNA libraries for an Illumina platform Fast: Procedure can be done in 4 hours Innovative method: Allows for rapid size-appropriate CpG-rich DNA fragment preparation and bisulfite conversion Highly Efficient: >99% conversion of unmethylated cytosine to uracil Convenient: Includes all necessary components Catalog #: P-1069