MMP9 Polyclonal Antibody

Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Description
MMP9 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
P14780

Purification
Affinity Purified

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human MMP9 (NP_004985.2)

Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.

Alternative Names
MMP9; CLG4B; GELB; MANDP2; MMP-9

Application
WB, IF; Recommended dilution: WB 1:500 - 1:2000, IF 1:50 - 1:200