BackgroundAdapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
DescriptionTTC5 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ8N0Z6
Purification>95%, Protein G purified
ImmunogenRecombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesTetratricopeptide repeat protein 5, TPR repeat protein 5, Stress-responsive activator of p300, Strap, TTC5
ApplicationELISA, WB; Recommended dilution: WB:1:1000-1:5000