BackgroundDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Methyl-CpG binding protein 2 (MeCP2), which can bind to methylated DNA in vivo and in vitro, may serve as a methylationdependent transcriptional repressor by association with known co-repressor proteins, which include members of the histone deacetylase protein families.
DescriptionMeCP2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityMouse, Rat
IsotypeIgG
Uniprot IDP51608
PurificationAffinity Purification
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1-100 of human MECP2 (NP_004983.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesAUTSX 3 antibody, DKFZp686A24160 antibody, Mbd 5 antibody, MECP 2 antibody, MeCP 2 protein antibody, MeCP2 antibody, Mecp2 antibody, MECP2_HUMAN antibody, Methyl CpG binding protein 2 (Rett syndrome) antibody, Methyl CpG binding protein 2 antibody, MRX 16 antibody, MRX 79 antibody, MRXS 13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, WBP 10 antibody
ApplicationWB; Recommended dilution: WB: 1:500-1:2000
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