TMPRSS2 Monoclonal Antibody

Background
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description
TMPRSS2 Monoclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
O15393

Purification
Affinity Purification

Immunogen
A synthesized peptide derived from human TMPRSS2

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
TMPRSS2, PP9284, PRSS10, transmembrane protease, serine 2, TMPRSS2, transmembrane protease, serine 2, transmembrane protease serine 2; epitheliasin; serine protease 10

Application
WB, IHC; Recommended dilution: WB: 1:500-1:2000, IHC: 1:50-1:200