Histone H4 along with H2A, H2B and H3 is involved in the structure of chromatin in eukaryotic cells. Histone H4 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications, including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H4, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H4 is primarily acetylated at lysine 5, 8, 12, and 16.
Histone H4K5ac (Acetyl H4K5) Polyclonal Antibody, unconjugated. Raised in: Rabbit
Human, Mouse, Rat, Monkey
Synthesized peptide derived from human Histone H4 around the acetylation site of K5.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Shipped at 4°C. Store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
H4K5ac antibody, H4K5a antibody
WB (1/500 - 1/2000), IHC (1/100 - 1/300), IF (1/200 - 1/1000), ELISA (1/10000)