We recommend our top selling Histone H4 Modification Multiplex Assay Kit to quantify 10 different histone H4 modifications.
BackgroundHistone H4 along with H2A, H2B and H3 is involved in the structure of chromatin in eukaryotic cells. Histone H4 can undergo several different types of epigenetic modifications that influence cellular processes. These modifications, including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation, occur on the N-terminal tail domains of histone H4, which results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. In most species, histone H4 is primarily acetylated at lysine 5, 8, 12, and 16.
DescriptionHistone H4K5ac (Acetyl H4K5) Polyclonal Antibody, unconjugated. Raised in: Rabbit
PurificationAffinity Purified
SpecificityHuman, Mouse, Rat, Monkey
ImmunogenSynthesized peptide derived from human Histone H4 around the acetylation site of K5.
Uniprot IDP62805
IsotypeIgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
StorageShipped at 4°C. Store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesH4K5ac antibody, H4K5a antibody
ApplicationELISA, IF, IHC, WB; Recommended dilution: WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000, ELISA:1:10000
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